Search Southern Minnesota hotels

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
10 Oct - 12 Oct
Next weekend
17 Oct - 19 Oct

Filter by

Guest rating
Guest rating
Star rating

Top hotels and accommodation in Southern Minnesota

Kahler Grand Hotel
Front of property – evening/night

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very good, (1646)
"Great location, beautiful hotel!"
Kahler Grand Hotel
AmericInn by Wyndham Rochester Near Mayo Clinic
Serves lunch, dinner and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

3.0 star property
8.2 out of 10, Very good, (1059)
"Great, inexpensive stay for mayo ..EXCELLENT STAFF!!"
The price is AU$130
includes taxes & fees
12 Oct - 13 Oct
AmericInn by Wyndham Rochester Near Mayo Clinic
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Front of property

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.2 out of 10, Good, (1003)
"Thank you for a quick check in, beautiful and clean rooms. "
The price is AU$125
includes taxes & fees
19 Oct - 20 Oct
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (835)
"Very convenient to Mayo clinic and good restaurants. "
The price is AU$136
includes taxes & fees
25 Oct - 26 Oct
Hotel Indigo Rochester – Mayo Clinic Area by IHG
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (914)
"Always stay here for my mayo visits "
The price is AU$187
includes taxes & fees
7 Nov - 8 Nov
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Aspen Suites
Exterior

Aspen Suites

3.0 star property
9.0 out of 10, Wonderful, (660)
"Great stay, breakfast options could use some work but waffle was great. "
Aspen Suites
Spark by Hilton Rochester South
Exterior

Spark by Hilton Rochester South

3.0 star property
9.4 out of 10, Exceptional, (199)
"Check in was easy and staff was extremely helpful! We'll definitely stay here again. "
The price is AU$127
includes taxes & fees
19 Oct - 20 Oct
Spark by Hilton Rochester South
AmericInn by Wyndham Lake City
Indoor pool

AmericInn by Wyndham Lake City

2.5 star property
9.0 out of 10, Wonderful, (609)
"Nice area, friendly and efficient staff and the rooms were very nice and were clean."
The price is AU$188
includes taxes & fees
2 Nov - 3 Nov
AmericInn by Wyndham Lake City
The Berkman
Terrace/patio

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (349)
"Perfect place to stay, very clean and easy access. "
The Berkman
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
In-room safe, desk, iron/ironing board, free cots/infant beds

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
7.8 out of 10, Good, (1007)
"Was a nice hotel for the money. Breakfast was great. "
The price is AU$114
includes taxes & fees
10 Oct - 11 Oct
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
AmericInn by Wyndham Winona
Exterior

AmericInn by Wyndham Winona

2.5 star property
9.0 out of 10, Wonderful, (851)
"We love the pet friendly aspect "
The price is AU$186
includes taxes & fees
26 Oct - 27 Oct
AmericInn by Wyndham Winona
Country Inn & Suites Rochester South Mayo Clinic
Property entrance

Country Inn & Suites Rochester South Mayo Clinic

3.0 star property
8.4 out of 10, Very good, (1002)
"A good place to stay."
The price is AU$149
includes taxes & fees
26 Oct - 27 Oct
Country Inn & Suites Rochester South Mayo Clinic
St James Hotel, a Historic Hotel of America
Exterior

St James Hotel, a Historic Hotel of America

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Love the historical hotel. Very clean and the staff was great. "
The price is AU$278
includes taxes & fees
12 Oct - 13 Oct
St James Hotel, a Historic Hotel of America
Days Inn by Wyndham Winona
Lobby

Days Inn by Wyndham Winona

2.0 star property
7.8 out of 10, Good, (1004)
"The room was very nice, bed was very comfortable, and the staff friendly."
The price is AU$115
includes taxes & fees
12 Oct - 13 Oct
Days Inn by Wyndham Winona
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lunch and dinner served, American cuisine

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
8.6 out of 10, Excellent, (1003)
"We stay here every year for the dog show. It's pet friendly and in a great location "
The price is AU$214
includes taxes & fees
9 Oct - 10 Oct
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Brentwood Inn & Suites
Desk, iron/ironing board, free WiFi, bed sheets

Brentwood Inn & Suites

2.5 star property
8.8 out of 10, Excellent, (1001)
"This hotel is very convenient and affordable for appointments at Mayo. "
The price is AU$196
includes taxes & fees
9 Oct - 10 Oct
Brentwood Inn & Suites
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Executive Room, 2 Queen Beds, Refrigerator & Microwave, Pool View (Living Room)

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

2.5 star property
8.2 out of 10, Very good, (740)
"staff was great no complaints room was phenomenal."
The price is AU$164
includes taxes & fees
12 Oct - 13 Oct
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Med City Inn & Suites - Mayo Clinic Area
Desk, laptop workspace, iron/ironing board, free WiFi

Med City Inn & Suites - Mayo Clinic Area

2.5 star property
7.8 out of 10, Good, (1001)
"Good location "
The price is AU$126
includes taxes & fees
21 Oct - 22 Oct
Med City Inn & Suites - Mayo Clinic Area
Aspen Select
Exterior

Aspen Select

3.5 star property
8.4 out of 10, Very good, (1003)
"Clean room | Staff was helpful and friendly"
Aspen Select
Residence Inn by Marriott Rochester Mayo Clinic Area South
BBQ/picnic Area

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
9.6 out of 10, Exceptional, (225)
"Great place"
The price is AU$197
includes taxes & fees
24 Oct - 25 Oct
Residence Inn by Marriott Rochester Mayo Clinic Area South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Great weekend hotel deals in Southern Minnesota, MN

Showing deals for:17 Oct - 19 Oct

Image gallery for Express Suites Riverport Inn & Suites

Lobby

Express Suites Riverport Inn & Suites

3.0 star property
Winona
8.4/10Very good (1,011 reviews)
10% off
Price is AU$561
for 2 nights, 1 room
AU$281 per night
includes taxes & fees
Express Suites Riverport Inn & Suites
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Central United States attractions

Mayo Civic Center

4.5/5 (411 reviews)
Catch an event at Mayo Civic Center during your trip to Rochester. Attend a sporting event or simply visit the area's shops.
See properties

Mayo Clinic Health System Event Center

4.3/5 (131 reviews)
Catch an event at Mayo Clinic Health System Event Center during your trip to Mankato. Discover the cafes and its entertainment venues while you're in the area.
See properties

Learn more about Southern Minnesota

Explore the family-friendly area of Southern Minnesota—an opera house, shopping and sights from Mount Kato Ski Area to Blakeslee Stadium.

See all hotels in Southern Minnesota
Rochester featuring skyline and a city
Photo by Howard Lower Photography
Open Photo by Howard Lower Photography

Top Southern Minnesota Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent
"Great, inexpensive stay for mayo ..EXCELLENT STAFF!!"
Beth 3-night trip
Posted 1 day ago
AmericInn by Wyndham Rochester Near Mayo Clinic

More cheap accommodation in Southern Minnesota

More cheap accommodation in Southern Minnesota

Redwood Lodge

Redwood Lodge

1382 E Bridge St, Redwood Falls, MN
The price is AU$153 per night from 6 Nov to 7 Nov
AU$153
6 Nov - 7 Nov
includes taxes & fees
8.8/10 Excellent! (699 reviews)

Explore a world of travel with Expedia

Explore a world of travel with Expedia